This Instant Pot Mississippi Pot Roast is the kind of meal that feels rich, comforting, and deeply satisfying with very little hands-on effort. It takes a classic slow-cooked favorite and transforms it into something you can make in just over an hour, without sacrificing flavor or tenderness.
The beef turns incredibly soft and juicy, practically falling apart with a fork. What makes this recipe stand out is the bold, savory gravy, buttery, slightly tangy, and packed with layers of flavor from pepperoncini, ranch seasoning, and au jus mix.
Every bite is rich and balanced, with just a hint of heat and acidity that keeps it from feeling too heavy. The Instant Pot locks in moisture and flavor, giving you that slow-cooked taste in a fraction of the time.
It’s a perfect meal for busy weeknights, cozy weekends, or when you need something reliable that feeds a crowd. Pair it with mashed potatoes or roasted vegetables, and you’ve got a complete comfort food dinner.
Why I Keep Making This Instant Pot Mississippi Pot Roast?
This is one of those recipes that delivers every single time. The meat comes out incredibly tender, and the gravy is so flavorful that it turns even simple sides into something special.
I love how hands-off it becomes after the initial searing. Once everything is in the pot, the pressure cooker does all the work, making it perfect for days when you don’t want to spend hours in the kitchen.
The flavor combination is another reason it’s on repeat. The tanginess from the pepperoncini, richness from the butter, and savory depth from the seasoning mixes create a unique taste that’s hard to beat.
It’s also very forgiving and flexible. You can adjust the spice level, add vegetables, or tweak the gravy thickness, and it still turns out great.
Most importantly, it’s a crowd-pleaser. Whether it’s a family dinner or meal prep for the week, this recipe always gets eaten and enjoyed.
Variations You Can Mess Around With
- Use a slow cooker instead of an Instant Pot for a traditional version.
- Add carrots and potatoes directly into the pot for a one-pot meal.
- Swap a chuck roast with brisket for a slightly different texture.
- Use low-sodium seasoning packets to control salt levels.
- Add mushrooms for extra depth and earthiness.
- Make it spicier by adding extra red pepper flakes.
- Shred the beef and use it for sandwiches or tacos.
Pro Tips for Perfect Results
- Sear the beef properly. This builds a deep, rich flavor base.
- Do not skip deglazing. This prevents burn warnings and adds flavor.
- Use natural pressure release. This keeps the meat tender and juicy.
- Cut the roast into large chunks. This helps it cook evenly.
- Use well-marbled beef. This ensures tenderness and flavor.
- Add butter in pieces. This helps it melt evenly into the sauce.
- Let the sauce simmer after cooking. This improves texture and thickness.
How to Make Instant Pot Mississippi Pot Roast?
Ingredients

- 5 lb chuck roast, cut into 2 chunks
- 3 tbsp vegetable or canola oil
- 1 small onion, diced
- 1 tbsp minced garlic
- 1/2 cup water
- 1/2 cup pepperoncini juice
- 3/4 cup beef broth
- 1 tbsp Worcestershire sauce
- 1/2 tsp salt
- 1/2 tsp black pepper
- 1/4 tsp red pepper flakes
- 1 packet dry ranch dressing mix
- 1 packet au jus mix
- 12 whole pepperoncinis
- 1 stick unsalted butter, sliced
- 8 cloves garlic, whole
- 5 bay leaves
Cornstarch slurry
- 2 to 3 tbsp cornstarch
- 3 tbsp water
Equipment
- Instant Pot
- Tongs
- Wooden spoon
- Mixing bowl
- Measuring cups and spoons
Instructions
Step 1:
Set the Instant Pot to saute mode and allow it to heat until it reaches the hot setting before adding oil.
Step 2:
Add the oil and sear the beef in batches, cooking each side undisturbed until a deep brown crust forms.

Step 3:
Transfer the browned beef to a plate and cover lightly to keep warm while finishing the rest.
Step 4:
Add water to the pot and scrape the bottom thoroughly with a wooden spoon to remove any browned bits.

Step 5:
Stir in the diced onion and minced garlic and cook briefly until fragrant and slightly softened.
Step 6:
Pour in the beef broth, pepperoncini juice, and Worcestershire sauce, then stir to combine.
Step 7:
Add salt, pepper, red pepper flakes, ranch mix, and au jus mix, stirring until everything is well incorporated.
Step 8:
Turn off sauté mode and return the beef to the pot, layering it with butter slices and whole garlic cloves.

Step 9:
Add the whole pepperoncinis and bay leaves, ensuring everything is evenly distributed.
Step 10:
Close the lid, seal the valve, and cook on high pressure until the beef becomes very tender.
Step 11:
Allow the pressure to release naturally for a period before carefully releasing any remaining pressure.
Step 12:
Open the lid and switch back to sauté mode if you want to thicken the sauce.
Step 13:
Mix cornstarch with water until smooth, then stir it into the pot and let the sauce simmer until thickened.

Step 14:
Remove bay leaves and serve the roast hot with your favorite sides and extra sauce.


Mississippi Pot Roast Recipe
Ingredients
Equipment
Method
- Set the Instant Pot to sauté mode and allow it to heat until it reaches the hot setting before adding oil.
- Add the oil and sear the beef in batches, cooking each side undisturbed until a deep brown crust forms.
- Transfer the browned beef to a plate and cover lightly to keep warm while finishing the rest.
- Add water to the pot and scrape the bottom thoroughly with a wooden spoon to remove any browned bits.
- Stir in the diced onion and minced garlic and cook briefly until fragrant and slightly softened.
- Pour in the beef broth, pepperoncini juice, and Worcestershire sauce, then stir to combine.
- Add salt, pepper, red pepper flakes, ranch mix, and au jus mix, stirring until everything is well incorporated.
- Turn off sauté mode and return the beef to the pot, layering it with butter slices and whole garlic cloves.
- Add the whole pepperoncinis and bay leaves, ensuring everything is evenly distributed.
- Close the lid, seal the valve, and cook on high pressure until the beef becomes very tender.
- Allow the pressure to release naturally for a period before carefully releasing any remaining pressure.
- Open the lid and switch back to sauté mode if you want to thicken the sauce.
- Mix cornstarch with water until smooth, then stir it into the pot and let the sauce simmer until thickened.
- Remove bay leaves and serve the roast hot with your favorite sides and extra sauce.
Notes
Nutrition Information
| Nutrient | Amount per Serving |
|---|---|
| Calories | 585 kcal |
| Carbohydrates | 6 gm |
| Fat | 38 gm |
| Protein | 55 gm |
Note: Nutritional values are approximate and may vary depending on ingredient size, quality, brand, location, and the proportions used. All nutritional information is calculated on a per-serving basis.
If you are following a medically restrictive diet, please consult your doctor or registered dietitian before preparing this recipe for personal consumption.
Common Mistakes to Avoid
- Skipping the searing step. This reduces flavor depth.
- Not deglazing the pot. This can trigger burn warnings.
- Using quick pressure release. This can dry out the meat.
- Overcrowding the pot. This prevents proper browning.
- Adding too much salt early. The seasoning packets already contain salt.
How I Like to Serve These
- Serve over creamy mashed potatoes.
- Pair with roasted vegetables for balance.
- Use leftovers in sandwiches or sliders.
- Serve with rice for a hearty meal.
- Add extra pepperoncinis for a tangy finish.
Storage / Leftovers and Next-Day Thoughts
- Store in an airtight container in the fridge.
- Keeps well for up to four days.
- Reheat gently on the stovetop for the best texture.
- Add a splash of broth when reheating to keep it moist.
- Freeze for longer storage if needed.
- Flavor deepens even more the next day.
FAQs
Can I use a different cut of beef?
Yes, but chuck roast works best because of its marbling and tenderness.
Can I skip the butter?
You can, but it adds richness and signature flavor to the dish.
Is this recipe spicy?
It has a mild kick, but you can adjust the heat level easily.
Can I make it ahead of time?
Yes, it reheats very well and tastes even better the next day.
Do I have to use both seasoning packets?
They are key to the classic flavor, but you can adjust to taste.



